Covaxin's booster dose demonstrates immunity, says Bharat Biotech

Pharmaceutical major Bharat Biotech on Wednesday said its COVID-19 vaccine Covaxin has proven to be safe, well-tolerated, and immunogenic in subjects in controlled clinical trials.

Coronavirus vaccines, booster shot
Photo: Bloomberg
Press Trust of India Hyderabad
2 min read Last Updated : Jul 20 2022 | 5:33 PM IST

Pharmaceutical major Bharat Biotech on Wednesday said its COVID-19 vaccine Covaxin has proven to be safe, well-tolerated, and immunogenic in subjects in controlled clinical trials.

The study has been accepted and published in Nature Scientific Reports, a high impact factor journal.

A press release from the vaccine maker said the study was conducted in 184 subjects, who were randomised 1:1 and received either a booster dose of Covaxin or a placebo, six months after the primary series of two doses.

Subjects were evaluated for safety, neutralising antibody responses against variants of concern, binding antibodies against spike protein, RBD, N proteins, and for memory T and B cell responses to demonstrate cell-mediated immunity, it said.

Krishna Ella, chairman and managing director, Bharat Biotech, said the team has now demonstrated that Covaxin is a multi-epitope vaccine with antibodies against spike, RBD and N proteins.

"Post booster dose, it has proven neutralising antibody responses against variants of concern and long term protection through memory T and B cell responses. We have now achieved our goal of developing a safe and efficacious vaccine with long-term protection against a spectrum of variants," Ella said.

Covaxin, is formulated uniquely such that the same dosage can be administered to adults and children alike, for primary and booster doses, making it truly a universal vaccine, the company release said.

The jab is a ready-to-use liquid vaccine, stored at 2-8 degrees Celsius, with 12-months shelf life and multi-dose vial policy.

Bharat Biotech has a stockpile of more than 50 million doses of Covaxin ready to be distributed as and when required.

(Only the headline and picture of this report may have been reworked by the Business Standard staff; the rest of the content is auto-generated from a syndicated feed.)

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Topics :Coronavirus VaccineCoronavirus Testscorona

First Published: Jul 20 2022 | 5:33 PM IST

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