"The reason we had the half-dose is serendipity," Mene Pangalos, the head of AstraZeneca's non-oncology research and development, told Reuters
Data from global trials to be submitted to the Indian regulator by the end of December
Poonawalla said the company will be able to produce 400 million doses of AstraZeneca's vaccine by July 2021 and scale up further from there
Serum Institute of India (SII) CEO Adar Poonawalla on Monday expressed happiness at pharma major AstraZeneca's announcement that its COVID-19 vaccine candidate has been found to be 70 per cent effective on average. AstraZeneca said one dosing regimen showed vaccine efficacy of 90 per cent when the vaccine was given as a half-dose followed by a full dose at least one month apart, while another dosing regimen showed 62 per cent efficacy when given as two full doses at least one month apart. "The combined analysis from both dosing regimens resulted in an average efficacy of 70 per cent," it added. In a tweet, Poonawalla said, "I am delighted to hear that, Covishield, a low-cost, logistically manageable & soon to be widely available, #COVID19 vaccine, will offer protection up to 90% in one type of dosage regime and 62% in the other dosage regime...". SII is currently conducting clinical trials of Oxford University-AstraZeneca's COVID-19 vaccine candidate in India. AstraZeneca also ...
Pfizer and Moderna may have an initial advantage in dealing with manufacturing challenges, as their novel messenger RNA technology can be scaled up.
AstraZeneca says late-stage trials of its Covid-19 vaccine were highly effective'' in preventing disease.
The company plans to keep the "active" drug substance in stock while it awaited regulatory approval around the world
The Astra-Oxford vaccine on average prevented 70% of cases in large trials in the U.K. and Brazil
The Astra vaccine costs a fraction of the price set by Pfizer; it should be easier to deploy far and wide than other shots.
The vaccine causes few side effects and provokes a response in T-cells that target the virus within 14 days of the first dose and a protective antibody response within 28 days of the booster dose
Even the front-runners among vaccine companies would take at least a few months to complete Phase-III trials and evaluate the efficacy and safety of individual vaccines
The Maharashtra government has said that the the second wave of coronavirus is expected in the state in January-February based on what is happening in Europe
AstraZeneca plans to start early and mid-stage clinical trials of its Covid-19 vaccine candidate in China this year, a senior executive said, as it prepares a global rollout of the vaccine
Product sales, which exclude payments from collaborations, rose 7 per cent to $6.52 billion for the three months ended September 30 on a constant-currency basis
Moderna and AstraZeneca are close behind the largest US drugmaker and are likely to have early data on their vaccine candidates before the end of the year.
If and when AstraZeneca reaches the first statistically reliable efficacy and safety results from those trials, based on more than 25,000 volunteers in total, it would present them to the US Food and
Drug firm AstraZeneca Pharma India on Thursday reported an 83.48 per cent rise in its net profit at Rs 26.33 crore for the quarter ended September 2020. The company had posted a net profit of Rs 14.41 crore for the corresponding period of the previous fiscal, it said in a filing to the BSE. Revenue from operations stood at Rs 209.47 crore for the quarter under consideration. It was Rs 208.48 crore for the same period a year ago, it added. Shares of AstraZeneca Pharma India closed at Rs4,295.80per scrip on the BSE, up 0.40 per cent from their previous close.
There are more than 200 candidates under development and the vaccine being developed by Oxford and licensed to British drugmaker AstraZeneca is seen as a front-runner
"We confirm the MHRA's (Medicines and Healthcare Products Regulatory Agency) rolling review of our potential Covid-19 vaccine," an AstraZeneca spokesman said
Moderna said earlier this month it was going to apply for real-time reviews of its experimental Covid-19 vaccine to Europe, following rolling reviews of shots of its rivals Pfizer Inc and AstraZeneca