Antibiotics

Don't use antibiotics in Covid till bacterial infection suspected: Govt

Antibiotics should not be used in Covid cases unless there is clinical suspicion of bacterial infection, according to a revised guideline for the treatment of adult coronavirus patients issued by the Centre. The revised guidelines, issued on Sunday amid an uptick in coronavirus cases, stated that drugs such as Lopinavir-ritonavir, hydroxychloroquine, Ivermectin, Molnupiravir, Favipiravir, Azithromycin and Doxycycline should not be used for the treatment of adult COVID-19 patients in India. The AIIMS/ICMR-COVID-19 National Task Force met on January 5 to revise the clinical guidance protocol. It has also advised doctors not to use convalescent plasma therapy. "Antibiotics should not be used unless there is clinical suspicion of bacterial infection. Possibility of co-infection of COVID-19 with other endemic infections must be considered," the guidelines said. Additionally, in moderate or severe diseases at high risk of progression, Remdesivir may be considered for up to five days. It

Glenmark Pharma receives USFDA approval for generic antibiotic drug

Glenmark Pharmaceuticals on Tuesday said it has received approval from the US health regulator to market a generic antibiotic drug. The company has received final approval from the US Food & Drug Administration (USFDA) for Clindamycin Hydrochloride Capsules, a generic version of Pfizer's Cleocin capsules, Glenmark Pharma said in a statement. Glenmark's Clindamycin Hydrochloride Capsules in strengths of 75 mg, 150 mg, and 300 mg, will be distributed in the US by Glenmark Pharmaceuticals Inc, it added. According to IQVIA sales data for the 12-month period ending January 2023, the Cleocin Hydrochloride Capsules, 75 mg, 150 mg, and 300 mg achieved annual sales of around USD 33.6 million. Glenmark shares were trading 0.12 per cent up at Rs 426.10 apiece on the BSE.

IMA advises against antibiotic use amid rising H3N2 flu cases in India

"Whenever there will be a real use of antibiotics, they will not work due to the resistance," the IMA wrote

Alkem launches novel antibiotic combination for drug-resistant infections

The formulation, to be sold under the Zidavi brans for Rs 2,700 a vial, has been approved by US FDA, European Medicines Agency, and CDSCO

WHO concerned over increasing antibiotic resistance in human infections

Countries with lower rates of testing, mostly low- and middle-income countries, are more likely to report significantly higher AMR rates

ICMR new guidelines warn against use of antibiotics for low-grade fever

The Indian Council of Medical Research has issued guidelines warning against the use of antibiotics for conditions such as low-grade fever and viral bronchitis while advising doctors to follow a timeline while prescribing them. The ICMR guidelines stated that antibiotics should be prescribed for a duration of five days for skin and soft tissue infections, five days in case of community-acquired pneumonia and eight days for hospital-acquired pneumonia. "A clinical diagnosis most often helps us predict causative pathogens fitting into a clinical syndrome which would tailor the correct antibiotic rather than blindly relying on fever, procalcitonin levels, WBC counts, cultures or radiology to make a diagnosis of infection," the guidelines said. It stated limiting empiric antibiotic therapy to seriously ill patients. Generally, empiric antibiotic therapy is only recommended for a select group of patients suffering from severe sepsis and septic shock, community-acquired pneumonia, ...

Orchid Pharma antibiotic product for treating UTI coming to India: MD

Company says it's returning to profit after takeover by Dhanuka Laboratories under insolvency resolution

India's first Covid cure Vincov-19 completes second phase clinical trial

Completes phase 2 trials successfully on 200 patients

NLEM: Several anti-cancer drugs, antibiotics to become more affordable

Thirty-four drugs, including some anti-infectives such as Ivermectin, Mupirocin and Nicotine Replacement Therapy, have been added to the National List of Essential Medicines taking the total drugs under it to 384. Several antibiotics, vaccines and anti-cancer drugs will become more affordable by their addition to the list. However, 26 drugs such as Ranitidine, Sucralfate, white petrolatum, Atenolol and Methyldopa have been deleted from the revised list. The deletion has been done based on the parameters of cost effectiveness and availability of better drugs. Union Health Minister Mansukh Mandaviya, who released the list on Tuesday, tweeted, "Released the National List of Essential Medicines 2022.It comprises 384 drugs across 27 categories.Several antibiotics, vaccines, anti-cancer drugs and many other important drugs will become more affordable & reduce patients' out-of-pocket expenditure." Endocrine medicines and contraceptives Fludrocortisone, Ormeloxifene, Insulin Glargine and

Antibiotics might worsen melanoma cancer by depleting gut microbiome: Study

According to a new study by researchers at Emory University in Atlanta, the use of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive form of skin cancer

Over 47% antibiotic formulations used by Indians in 2019 unapproved: Study

More than 47 per cent of antibiotic formulations used in India's private sector in 2019 were not approved by the central drug regulator, according to a study published in The Lancet Regional Health-Southeast Asia. The research also found that Azithromycin 500mg tablet was the most consumed antibiotic formulation (7.6 per cent) in India, followed by cefixime 200 mg tablet (6.5 per cent) during the year. The researchers at Boston University, US and Public Health Foundation of India, New Delhi, examined the private sector antibiotic use, which contributes to 8590 per cent of the total consumption in India. The data were gathered from a panel of 9,000 stockists who store products from approximately 5,000 pharmaceutical companies. However, these data did not include the drugs dispensed through public facilities, though this is less than 1520 per cent of all drug sales in the country as per studies and national health accounts estimates. The researchers found a lower consumption rate of

Wockhardt initiates phase-III clinical study of new antibiotic candidate

Pharmaceutical firm Wockhardt Ltd on Tuesday said it has initiated a global Phase III clinical study of its new antibiotic candidate WCK 5222, which will be completed in 18 months

Effect of common Covid-19 antibiotic found similar to that of placebo

The findings of a new study from UC San Francisco suggests that among non-hospitalized patients the antibiotic azithromycin was no more effective than a placebo in preventing symptoms of Covid-19

Misuse of antibiotics soared in India during Covid pandemic: Study

Covid-19 likely contributed to 216.4 million excess doses of antibiotics for adults: study

Zydus Cadila seeks regulator nod for clinical trials on Covid-19 therapy

Company says product helps treating mild coronavirus patients and reduces hospitalisation.

Decoded: What is black fungus and its link to Covid-19 pandemic

India has a huge diabetic population that is at risk. And along with that, steroids and antibiotics are being used quite irrationally for Covid-19 patients

Domestic drug market growth slows top 4.5% in January, some therapies drag

Respiratory segment and anti-infectives contract; Cardiac, anti-diabetic growth rates plummet

Antibody stops responding to virus over time: Covid vaccine under scrutiny

The study suggests that antibodies, a marker of exposure to the coronavirus, may not be lasting in all people

Human antibody that may limit the spread of coronavirus identified

The Covid-19 pandemic has spread rapidly across the globe infecting more than 3.3 million people worldwide

Antibiotic sales drive domestic pharma mkt down 11.2% in lockdown-hit April

Sale of anti-infectives (11% of domestic pharma market) fell by 21.5%, while gynaecological and dermatological drugs fell by about 23%