At closing bell, the 225-issue Nikkei Stock Average index declined by 139.28 points, or 0.49%, to 28,313.47. The broader Topix index of all First Section issues on the Tokyo Stock Exchange dropped by 4.26 points, or 0.22%, to 1,967.18.
Tech stocks were hit hard, with Screen Holdings and Tokyo Electron losing 1-2%. Video game company Konami lost 2.8% and Nintendo fell 2.6%.
Energy stocks outperformed, with Inpex Corp adding 1.7%. Tokyo Electric jumped 10% after reports that the government wants to restart more nuclear reactors to avoid power shortages.
Olympus soared 2.7% after a report said Bain Capital was the frontrunner to buy its scientific optics unit for about 400 billion yen.
Toyota was down 0.4% after a report said it had backed down in a fight against California car emission rules.
Sumitomo Mitsui Financial Group was up 1% after a report said the banking group plans to start an online lending venture in the United States.
CURRENCY NEWS: The dollar fell to around mid-136 yen in Tokyo trading on Wednesday, weighed on by concerns over the U.S. economy and the Ukraine situation. At 5 p.m., the dollar stood at 136.54-55 yen, down from 137.27-28 yen at the same time Tuesday. The euro was at 0.9953-9953 dollars, up from 0.9933-9934 dollars, and at 135.91-91 yen, down from 136.35-36 yen.
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