"Traders are expecting more bouts of volatility in coming sessions on concerns that continuation of rate hikes in the US could pose a threat to the global economy and hurt growth prospects," Shrikant Chouhan, Head of Equity Research (Retail), Kotak Securities Ltd, said.
Tech Mahindra was the biggest laggard in the Sensex pack, falling 4.57 per cent, followed by Infosys, Wipro, HCL Technologies, Tata Consultancy Services, Kotak Mahindra Bank, Tata Steel, Axis Bank, ICICI Bank and State Bank of India.
On the other hand, Maruti, Asian Paints, Nestle, ITC, M&M and Hindustan Unilever were among the gainers.
Elsewhere in Asia, markets in Seoul, Tokyo, and Hong Kong settled lower, while Shanghai ended marginally higher.