Brain Cells

Scientists have uncovered details regarding an immune response to a virus present in all human tissues, that kicks in in the elderly and eliminates senescent, or aging, cells in the skin. Senescent cells are those that stop dividing but do not die, accumulating in the body over time, fuelling chronic inflammation and contributing to conditions such as cancer and degenerative disorders. Eliminating senescent cells from aging tissues has been found to restore tissue balance in mice, leading to an increased healthy lifespan. When a team of scientists, led by Massachusetts General Hospital (MGH), US, found that the number of senescent cells in samples from old individuals did not increase as the individuals got older, they realised that there is some mechanism kicking in to keep the aging in check. The scientists have described their findings in the journal Cell. Experiments have proved that in the elderly, certain immune cells called killer CD4+ T cells keep senescent cells from ...

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